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Dynamic Atlas-Based Segmentation and Quantification of Neuromelanin-Rich Brainstem Structures in Parkinson Disease

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Abstract:          Parkinson’s disease (PD) is a neurodegenerative disease histo-pathologically characterized by neuronal loss, Lewy bodies, and depigmentation of two paired neuromelanin (NM) rich brainstem structures: the substantial nigra pars compacta (SNc) and the locus coeruleus (LC). In spite of th..

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